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If we had the technology than can measure specific biomolecules inside of bodies in “real time”, it would transform medicine by providing clinicians with a valuable window into patients’ health and their response to therapies. Unfortunately, such real-time measurements are currently not possible, except for a handful of molecules such as glucose. In this presentation, we will discuss recent advancements in “real-time biosensors.” As examples, we will present our group’s work on continuously measuring anti-cancer and anti-bacterial drugs in live animals with unprecedented time-resolution. Finally, we will discuss the exciting possibility of actively controlling these molecules inside of patients using closed-loop feedback control.
Dr. Soh is a Professor at Stanford University with a joint appointment in Electrical Engineering and Radiology. He received his B.S. with a double major in Mechanical Engineering and Materials Science with Distinction from Cornell University, and Ph.D. in Electrical Engineering from Stanford. Prior to joining Stanford in 2015, he was the Ruth Garland professor at UC-Santa Barbara. His research group develops novel biomaterials and molecular measurement techniques for medical diagnostics. He is the recipient many awards including MIT Technology Review’s "TR 100 Innovator" Award, ONR Young Investigator Award, Beckman Young investigator award, NIH TR01 Award, John Simon Guggenheim Fellowship and Alexander von Humboldt Fellowship.
